As a major contributor to the ongoing life sciences research and development, you must be dealing with huge Biological databases. Research indicates that the modern day pharmaceutical and biotechnology companies have about Tera Bytes (TB) of information depending on their needs. The wealth of this scientific data can only be unleashed when it is intelligently integrated and computed. In order to keep you focused on your research, Best Biotek extends its hand in partnership to develop appropriate solutions.

Best Biotek in to following Bioinformatics Solutions

·        Developing of Biological Sotware

o       Bioinformatics

o       Chemical informatics

·        Software Testing

·        Data Mining & Curation

·        Consulting and Solution

DEVELOPING OF BIOLOGICAL SOFTWARE

Bioinformatics Application and Developments are challenging area in all the fields of Life sciences. It is fascinating for the combinatorial chemistry, for instance, is focused to expand chemistry space for molecules and lead optimization is focused to cherry pick the lead molecules. Fortunately, the coming together of scientific research and software development has made it all possible.

Software development services in Bioinformatics Application and Developments are designed to:

• Biological Research Enhancing, Time and cost Saving
• Increase consistency in data storage & retrieval
• Streamline chemical structure drawing process
• Drive dimensionality reduction of analysis
• Enhance in-silico screening, synthesis and modeling
• Unify genomics and proteomics research techniques
• Streamline workflows and enable better laboratory management

Best Biotek offers a wide range of Biosoftware development services for Cheminformatics and Bioinformatics

·        Software for Chemical Structure

·        Database Conversion, integration

·        Molecular Structure Drawing &Visualization

·        Chemistry Database creation

·        Diversity Analysis &Clustering

·        Combinatorial Chemistry Tools

·        Structure Property Calculator

·        ADME/Toxicity Property Calculator

·        Data Management and Analysis Modules

·        Analytical Platform Solutions

·        Algorithm Development

·        Laboratory Information Management System (LIMS)

SOFTWARE TESTING

Our software testing services are focused to validate scientific correctness and identify performance, functionality and compatibility related bottlenecks and bugs. Our comprehensive testing services including:

• Test planning, test case development
• Test automation, script development and execution
• Performance, load and stress testing, script development and execution
• Localization testing
• Functionality testing
• Configuration/Compatibility testing
• Installation testing
• Web-based defect tracking and management
• Compliance Certification testing

DATA MINING & CURATION

Modern Biology, chemistry techniques and practices generate outsized amount of data and huge number of chemical compounds. As a consequence, one of the biggest challenges is to tag all of the available information so they can analyze and generate knowledge from it. We have identified the importance of data management and offers following curation and database services. We helps you in curation of Chemical, Biological, Pre-Clinical, Clinical and ADME/Toxicology databases. We use multiple source including, patents, journals and other sources of literature. These Databases can add value to the ongoing target identification, lead identification and lead optimization in your drug discovery programs. Our data curation services are focused to create reusable knowledgebase. The following table indicates the key parameters that we identified with respect to chemical, biological, pharmacology and bibliographic databases:

We have identified some of the important databases that we can curate:

• Small molecule databases with biological, pharmacological activities
• Known drugs database
• Reaction databases
• Toxicology database
• Clinical, pre-clinical database
• Gene/protein/mutant/pathway centric database with development of controlled vocabularies, allied interfaces and validating them against GO, TO ontologies
• Protein-protein interactions, QTLs, gene/protein families, biomarkers, expression/toxicology profiling and synteny databases to understand the conservation across different systems
• Metabolic pathway databases - support with microarray-analyzed expression profiling, custom tool development for drawing pathways and link them to various sources
• Custom newsletters subscription – Screen, compile and publish custom alerts with latest published information on important candidate genes and other client specific requirements

Databases can also be customized as per your requirements. We have identified some of your critical needs and recommend using the following database services:

CONSULTING AND SOLUTION

Biopharmaceutical companies constantly face technology and manpower challenges. One, drug discovery involves usage of expensive analytical tools and technologies that are difficult to acquire. Two, it is not uncommon to find shortage of skills to work on these technologies.

We has both technology and highly qualified chemists and biologists to address these challenges. We provide offshore services, for instance, to develop new lead molecules for desired target using our in-house technologies. We can also provide on-site services if you have tools that are inadequately equipped with manpower. Even as we deliver these services, we ensure that Intellectual Properties (IPs) of our clients are protected. We has state-of-art facility and also stringent processes to maintain confidentiality across projects

Bioinformatics

Pharmacogenomics data requires intensive analysis and validation. A large volume of data comes in and out of innumerous laboratory experiments. Best Biotek offers consulting services in data analysis of the following:

• Genomics and Proteomics
• Pharmacogenomics /Toxicogenomics
• Proteonomics
• Structural/ Functional Genomics
• Gene Expression/finding/Prediction etc.,

Cheminformatics

We built strong capabilities to expedite your lead identification and optimization at reduced costs. Our domain expertise spans both structure-based and analog-based drug design. We provide services in virtual Ligand screening, molecular diversity analysis/clustering and ADMET Modeling.

·        Structure Data Conversion

·        QSAR & Docking for Drug Design

·        Structure-based Drug Design

·        High throughput screening

·        Receptor - Ligand Interaction

·        Structure Data Analysis

·        ADME-T Prediction & Modeling

SOFTWARE REQUIREMENT

Platform

            MS. Windows

            Linux

            SUN Solaris

Tools for Project Management

            XPlanner

            MS. Project

            Visual SourceSafe

            Rational

Tools for Software Development

            .NET

            SAS 9

            JAVA/J2EE

            Developer 2000

            PERL

Tools for Testing

            Winrunner

            Loadrunner

            Silk Test

            QTP 8.2

            Rose Testing

Tools for Data Curation/Mining

            SAS 9

            SPSS 14.0

            Oracle 9i

            My SQL

Tools for Consulting